What are the consequences of excessive folic acid supplementation in hypertension?
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Core tips: Nowadays, the number of patients with hypertension is increasing, which has become the largest chronic disease endangering the national health of our country. The characteristics of hypertension are not obvious. Emotional excitement and forced defecation can easily lead to a sudden rise in blood pressure, cerebral infarction, cerebral hemorrhage, and other accidents. One person gets sick, and the whole family is affected. Therefore, the prevention and treatment of hypertension are very important.
Nowadays, the number of patients with hypertension is increasing day by day, which has become the largest chronic disease endangering China's national health. Moreover, the characteristics of hypertension are not obvious. Emotional excitement and forced defecation can easily lead to the sudden rise of blood pressure, cerebral infarction, cerebral hemorrhage, and other accidents. One person gets sick and the whole family is affected. Therefore, the prevention and treatment of hypertension are very important.
Why do hypertensive patients need folic acid?
Folic acid belongs to B vitamins, also known as vitamin B11. It is a kind of vitamin to maintain cell function, metabolism, and growth. It is important for the synthesis of nucleic acid and protein, the mutual transformation of amino acids, purine synthesis, and DNA synthesis and metabolism.
There is a type of hypertension called "H-type hypertension". Here, H actually refers to the first letter of homocysteine, because the lack of homocysteine is the reason for the increase of H-type hypertension. According to the survey, 75% of the existing adult patients with hypertension are H-type hypertension with elevated homocysteine.
Folic acid and homocysteine metabolism are closely related. Homocysteine is a sulfur-containing amino acid formed in the methionine metabolism pathway in the body. Under the action of folic acid, homocysteine can resynthesize methionine, and the content of homocysteine in the plasma will be reduced. On the contrary, if the body lacks folic acid, it will lead to the blocked synthesis of homocysteine and form high homocysteine Aminoacidemia.
Hyperhomocysteinemia can cause damage to vascular endothelial cells and vascular smooth muscle, affect the process of vascular movement, change the elasticity of the arterial wall, lead to rapid contraction of blood vessels, cause atherosclerotic thrombosis, and induce cerebral infarction and myocardial infarction. At the same time, H-type hypertension patients with elevated homocysteine are more likely to have a stroke.
Therefore, patients with hypertension need to check the level of folic acid in time, if the lack of appropriate supplements to prevent myocardial infarction, cerebral infarction, and other cardiovascular and cerebrovascular diseases.
What are the consequences of folic acid overdose?
If the body lacks folic acid, it is recommended to supplement food. Foods rich in folic acid include green leafy vegetables, carrots, egg yolks, pumpkins, beans, etc. If the effect of food supplements is not obvious, or the lack is serious, drug supplements can be carried out under the guidance of doctors.
But it should be noted that folic acid is not the more the better. Excessive intake of folic acid will affect the absorption of vitamin B12, especially for the elderly who lack vitamin B12. If a large amount of folic acid is added blindly, it will cover up the deficiency of vitamin B12 caused by pernicious anemia, which will damage nerves and cause serious harm to health for a long time.
Therefore, whether folic acid is deficient and whether it needs to be supplemented can only be known after going to the hospital for examination. You can't eat folic acid tablets as health care products. It's very dangerous to eat folic acid tablets when you feel that you lack them. If you are worried about cardiovascular and cerebrovascular diseases, you can eat more food rich in folic acid and check the folic acid level in the hospital regularly.
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